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Article

Correlation between Ca(2+) oscillation and cell proliferation via CCK(B)/gastrin receptor.

Biochimica et biophysica acta - 9 Dec 1999

Akagi K, Nagao T, Urushidani T

Abstract excerpt

Gastrin stimulates cell proliferation through the CCK(B) receptor coupled to Gq-protein, whereas the m3 muscarinic receptor, which also couples to Gq, has no trophic effects. In order to elucidate the cause of the difference, we stably transfected CHO cells with human CCK(B) and m3 receptors. Stimulation of the CCK(B), but not the m3 receptor increased cell growth. Activation of MAP kinase via the m3 receptor was...

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Source

Identifiers

PMID: 10590313
DOI: 10.1016/s0167-4889(99)00137-8

Genes

CCK

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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