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Article

Quantitative Immunohistochemistry by Measuring Cumulative Signal Strength Accurately Measures Receptor Number

1 Feb 2003

Abstract excerpt

We previously demonstrated that quantitative immunohistochemistry (Q-IHC) performed by measuring the cumulative signal strength of the digital file encoding an image can be used to determine the absolute amount of chromogen present per pixel. We now show that Q-IHC so performed can be used to accurately determine the amount of peptide hormone receptor of interest in archived tissues. To do this we transfected...

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PMID: 12533529
DOI: 10.1177/002215540305100209

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