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Article

Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex.

Biophysical journal - 1 Jul 2005

Bowen Mark E, Weninger Keith, Ernst James, Chu Steven, Brunger Axel T

Abstract excerpt

The assembly of multiprotein complexes at the membrane interface governs many signaling processes in cells. However, very few methods exist for obtaining biophysical information about protein complex formation at the membrane. We used single molecule fluorescence resonance energy transfer to study complexin and synaptotagmin interactions with the SNARE complex in deposited lipid bilayers. Using total internal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15821166
DOI: 10.1529/biophysj.104.054064
PMCID: PMC1366567

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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