Article
Dance of the SNAREs: assembly and rearrangements detected with FRET at neuronal synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Mar 2013
Degtyar Vadim, Hafez Ismail M, Bray Christopher, Zucker Robert S
Abstract excerpt
Soluble N-ethylmaleimide-sensitive fusion protein attachment protein receptors (SNAREs) mediate vesicle fusion with the plasma membrane on activation by calcium binding to synaptotagmin. In the present study, we used fluorescence resonance energy transfer (FRET) and fluorescence lifetime imaging microscopy between fluorescently labeled SNARE proteins expressed in cultured rat hippocampal neurons to detect resting...
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