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Article

Synaptotagmin oligomerization is essential for calcium control of regulated exocytosis.

Proceedings of the National Academy of Sciences of the United States of America - 7 Aug 2018

Bello Oscar D, Jouannot Ouardane, Chaudhuri Arunima, Stroeva Ekaterina, Coleman Jeff, Volynski Kirill E, Rothman James E, Krishnakumar Shyam S

Abstract excerpt

Regulated exocytosis, which underlies many intercellular signaling events, is a tightly controlled process often triggered by calcium ion(s) (Ca2+). Despite considerable insight into the central components involved, namely, the core fusion machinery [soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)] and the principal Ca2+ sensor [C2-domain proteins like synaptotagmin (Syt)], the...

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Identifiers

PMID: 30038018
DOI: 10.1073/pnas.1808792115
PMCID: PMC6094142

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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