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Article

Power and sample size calculations in the presence of phenotype errors for case/control genetic association studies.

BMC genetics - 8 Apr 2005

Edwards Brian J, Haynes Chad, Levenstien Mark A, Finch Stephen J, Gordon Derek

Abstract excerpt

BACKGROUND: Phenotype error causes reduction in power to detect genetic association. We present a quantification of phenotype error, also known as diagnostic error, on power and sample size calculations for case-control genetic association studies between a marker locus and a disease phenotype. We consider the classic Pearson chi-square test for independence as our test of genetic association. To determine...

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Identifiers

PMID: 15819990
DOI: 10.1186/1471-2156-6-18
PMCID: PMC1131899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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