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Article

The effects of SNP genotyping errors on the power of the Cochran-Armitage linear trend test for case/control association studies.

Annals of human genetics - 1 Mar 2007

Ahn Kwangmi, Haynes Chad, Kim Wonkuk, Fleur Rose St, Gordon Derek, Finch Stephen J

Abstract excerpt

The questions addressed in this paper are: What single nucleotide polymorphism (SNP) genotyping errors are most costly, in terms of minimum sample size necessary (MSSN) to maintain constant asymptotic power and significance level, when performing case-control studies of genetic association applying the Cochran-Armitage trend test? And which trend test or chi2 test is more powerful under standard genetic models...

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PMID: 17096677
DOI: 10.1111/j.1469-1809.2006.00318.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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