Article
Quantification of the power of Hardy-Weinberg equilibrium testing to detect genotyping error.
Human heredity - 1 Jan 2006
Cox David G, Kraft Peter
Abstract excerpt
Deviation from Hardy-Weinberg equilibrium has become an accepted test for genotyping error. While it is generally considered that testing departures from Hardy-Weinberg equilibrium to detect genotyping error is not sensitive, little has been done to quantify this sensitivity. Therefore, we have examined various models of genotyping error, including error caused by neighboring SNPs that degrade the performance of...
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