Article
Allowing for genotyping error in analysis of unmatched case-control studies.
Annals of human genetics - 1 Mar 2003
Rice K M, Holmans P
Abstract excerpt
A commonly-used method for testing for association between disease and a single-nucleotide polymorphism (SNP) is to compare the frequencies of the SNP genotypes in a sample of unrelated cases to those in a sample of unrelated controls drawn from the same population (an unmatched case-control study). A drawback of such a study is that it is impossible to detect genotyping errors, and few methods have been...
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