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Article

Novel genetic analysis for case-control genome-wide association studies: quantification of power and genomic prediction accuracy.

PloS one - 1 Jan 2013

Lee Sang Hong, Wray Naomi R

Abstract excerpt

Genome-wide association studies (GWAS) are routinely conducted for both quantitative and binary (disease) traits. We present two analytical tools for use in the experimental design of GWAS. Firstly, we present power calculations quantifying power in a unified framework for a range of scenarios. In this context we consider the utility of quantitative scores (e.g. endophenotypes) that may be available on cases only...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23977056
DOI: 10.1371/journal.pone.0071494
PMCID: PMC3747270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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