Quantifying the percent increase in minimum sample size for SNP genotyping errors in genetic model-based association studies.

Abstract excerpt

Kang et al. [Genet Epidemiol 2004;26:132-141] addressed the question of which genotype misclassification errors are most costly, in terms of minimum percentage increase in sample size necessary (%MSSN) to maintain constant asymptotic power and significance level, when performing case/control studies of genetic association in a genetic model-free setting. They answered the question for single nucleotide...

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