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Article

A cost-effective statistical method to correct for differential genotype misclassification when performing case-control genetic association.

Human heredity - 1 Jan 2010

Londono Douglas, Haynes Chad, De La Vega Francisco M, Finch Stephen J, Gordon Derek

Abstract excerpt

BACKGROUND/AIMS: There is a growing interest regarding the effect of differential misclassification on power and type I error rate in genome-wide association studies. We present an extension of a previously published test statistic: the likelihood ratio test allowing for errors (LRTAE). This test uses double-sample information on a subset of individuals to increase power for genetic association in the presence of...

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PMID: 20606457
DOI: 10.1159/000314470

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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