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Article

Characterization of a cyclooxygenase-2-765G-->C promoter polymorphism in human neural cells.

Neuroreport - 25 Apr 2005

Cui Jian-Guo, Salehi-Rad Shabnam, Rogaeva Ekaterina, Lukiw Walter J

Abstract excerpt

Direct sequencing of the human cyclooxygenase-2 gene promoter revealed a common single nucleotide substitution, cyclooxygenase-2-765G-->C, in 24.5% of the populations analyzed. This change introduced a 20 base pair polypyrimidine/polypurine element and a partial recognition feature for RXRalpha, the 9-cis retinoic acid receptor, into the polymorphic promoter. Cyclooxygenase-2-765G-->C constructs, when transfected...

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Identifiers

PMID: 15812311
DOI: 10.1097/00001756-200504250-00012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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