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Article

Cyclooxygenase-2-765G>C functional promoter polymorphism and its association with oral squamous cell carcinoma.

Journal of investigative and clinical dentistry - 1 Aug 2012

Lakshmi Addala, Muralidhar Sadhnani, Kalyan Kumar Chennaboina, Pavan Kumar Addala, Kalyana Chakravarthy Pentapati, Anjaneyulu Vasala, Kaiser Jamil

Abstract excerpt

AIM: Cyclooxygenase-2 is a key enzyme in the conversion of arachidonic acid to prostaglandins, and has critical role in the progression of several malignancies, including oral squamous cell carcinoma. METHODS: We designed a case-control study to evaluate the susceptibility of the functional -765G>C genetic variation in oral squamous cell carcinoma patients. Polymerase chain reaction-based restriction fragment...

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Identifiers

PMID: 22887904
DOI: 10.1111/j.2041-1626.2011.00104.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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