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Article

Functional significance of gene polymorphisms in the promoter of myeloid differentiation-2.

Annals of surgery - 1 Jul 2007

Gu Wei, Shan You-an, Zhou Jian, Jiang Dong-po, Zhang Lianyang, Du Ding-yuan, Wang Zheng-guo, Jiang Jian-xin

Abstract excerpt

OBJECTIVE: To investigate the functional significance of the reported single nucleotide polymorphisms (SNPs) in the promoter of the myeloid differentiation-2 (MD-2) gene. SUMMARY BACKGROUND DATA: Functional gene polymorphisms of innate immune receptors have been shown to be critical determinants of the immune inflammatory response. MD-2 is an important signaling enhancer protein in the endotoxin (LPS) receptor...

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Identifiers

PMID: 17592304
DOI: 10.1097/01.sla.0000262788.67171.3f
PMCID: PMC1899213

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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