Article
The apolipoprotein E epsilon4 allele and incident Alzheimer's disease in persons with mild cognitive impairment.
Neurocase - 1 Feb 2005
Aggarwal Neelum T, Wilson Robert S, Beck Todd L, Bienias Julia L, Berry-Kravis Elizabeth, Bennett David A
Abstract excerpt
Possession of one or more copies of the apolipoprotein E (APOE) epsilon4 allele is a known risk factor for Alzheimer's disease (AD), but it is uncertain whether the epsilon4 allele is associated with disease incidence among persons with mild cognitive impairment (MCI). We addressed this issue wit...
Topics
- Aged
- Aged, 80 and over
- Alzheimer Disease
- Apolipoprotein E4
- Apolipoproteins E
- Clergy
- Cognition Disorders
- Confidence Intervals
- Female
- Genotype
- Humans
- Incidence
- Longitudinal Studies
- Male
- Neuropsychological Tests
- Proportional Hazards Models
- Psychiatric Status Rating Scales
- Risk