Article
Predictive utility of apolipoprotein E genotype for Alzheimer disease in outpatients with mild cognitive impairment.
Archives of neurology - 1 Jun 2005
Devanand D P, Pelton Gregory H, Zamora Diana, Liu Xinhua, Tabert Matthias H, Goodkind Madeleine, Scarmeas Nikolaos, Braun Ilana, Stern Yaakov, Mayeux Richard
Abstract excerpt
BACKGROUND: In cognitively impaired patients without dementia, the utility of apolipoprotein E (APOE) genotyping is unclear. OBJECTIVE: To evaluate the predictive utility of the APOE epsilon4 genotype for conversion to probable Alzheimer disease (AD). DESIGN: Naturalistic, longitudinal study. SETTING: Memory disorders outpatient clinic. PATIENTS: A total of 136 patients with memory complaints were determined to...
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