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Article

Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 30 Mar 2005

Winks Joanna S, Hughes Simon, Filippov Alexander K, Tatulian Lucine, Abogadie Fe C, Brown David A, Marsh Stephen J

Abstract excerpt

The relationship between receptor-induced membrane phosphatidylinositol-4'5'-bisphosphate (PIP2) hydrolysis and M-current inhibition was assessed in single-dissociated rat sympathetic neurons by simultaneous or parallel recording of membrane current and membrane-to-cytosol translocation of the fluorescent PIP2/inositol 1,4,5-trisphosphate (IP3)-binding peptide green fluorescent protein-tagged pleckstrin homology...

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Source

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Identifiers

PMID: 15800195
DOI: 10.1523/JNEUROSCI.3231-04.2005
PMCID: PMC6724893

Genes

KCNQ2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Relationship between membrane phosphatidylinositol-4,5-bisphosphate and receptor-mediated inhibition of native neuronal M channels.PMID 15800195Read ↗

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