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Article

PIP2 and PIP as determinants for ATP inhibition of KATP channels.

Science (New York, N.Y.) - 6 Nov 1998

Baukrowitz T, Schulte U, Oliver D, Herlitze S, Krauter T, Tucker S J, Ruppersberg J P, Fakler B

Abstract excerpt

Adenosine triphosphate (ATP)-sensitive potassium (KATP) channels couple electrical activity to cellular metabolism through their inhibition by intracellular ATP. ATP inhibition of KATP channels varies among tissues and is affected by the metabolic and regulatory state of individual cells, suggesting involvement of endogenous factors. It is reported here that phosphatidylinositol-4, 5-bisphosphate (PIP2) and...

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Source

Identifiers

PMID: 9804555
DOI: 10.1126/science.282.5391.1141

Genes

PIP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

PIP2 and PIP as determinants for ATP inhibition of KATP channels.PMID 9804555Read ↗

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The Pharmacology of ATP-Sensitive K+ Channels (KATP).Semantic proximity Read ↗

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Molecular determinants of KATP channel inhibition by ATP.Semantic proximity Read ↗

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Molecular biology of K(ATP) channels and implications for health and disease.Semantic proximity Read ↗

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Kir6.2 polymorphisms sensitize beta-cell ATP-sensitive potassium channels to activation by acyl CoAs: a possible cellular mechanism for increased susceptibility to type 2 diabetes?Semantic proximity Read ↗

Differential response of K(ATP) channels containing SUR2A or SUR2B subunits to nucleotides and pinacidil.Semantic proximity Read ↗

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