Article
PIP2 and PIP as determinants for ATP inhibition of KATP channels.
Science (New York, N.Y.) - 6 Nov 1998
Baukrowitz T, Schulte U, Oliver D, Herlitze S, Krauter T, Tucker S J, Ruppersberg J P, Fakler B
Abstract excerpt
Adenosine triphosphate (ATP)-sensitive potassium (KATP) channels couple electrical activity to cellular metabolism through their inhibition by intracellular ATP. ATP inhibition of KATP channels varies among tissues and is affected by the metabolic and regulatory state of individual cells, suggest...
Topics
- ATP-Binding Cassette Transporters
- Adenosine Triphosphate
- Animals
- Cloning, Molecular
- Diazoxide
- Dose-Response Relationship, Drug
- Mutation
- Oocytes
- Patch-Clamp Techniques
- Phosphatidylinositol 4,5-Diphosphate
- Phosphatidylinositol Phosphates
- Phosphatidylinositols
- Potassium Channel Blockers
- Potassium Channels
- Potassium Channels, Inwardly Rectifying
- Receptors, Drug
- Receptors, Purinergic P2
- Receptors, Purinergic P2Y2