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Article

Homozygous Ft embryos are affected in floor plate maintenance and ventral neural tube patterning.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2005

Götz Katrin, Briscoe James, Rüther Ulrich

Abstract excerpt

Sonic hedgehog (Shh), produced by the notochord and floor plate cells of the neural tube, plays a critical role in organizing dorsal-ventral patterning in the developing neural tube. We have investigated neural tube development in mouse embryos homozygous for the Fused toes (Ft) mutation, a deletion composed of genes of the Iroquois B (IrxB) cluster and of Fts, Ftm, and Fto. In Ft mutants starting from embryonic...

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Identifiers

PMID: 15789444
DOI: 10.1002/dvdy.20354

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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