Article
Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes.
Developmental biology - 1 Apr 2007
Anselme Isabelle, Laclef Christine, Lanaud Magali, Rüther Ulrich, Schneider-Maunoury Sylvie
Abstract excerpt
During vertebrate development, brain patterning and head morphogenesis are tightly coordinated. In this paper, we study these processes in the mouse mutant Fused toes (Ft), which presents severe head defects at midgestation. The Ft line carries a 1.6-Mb deletion on chromosome 8. This deletion eliminates six genes, three members of the Iroquois gene family, Irx3, Irx5 and Irx6, which form the IrxB cluster, and...
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