Article

Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve ganglia

2023-08-04

Abstract excerpt

<h4>ABSTRACT</h4> The formation of the brain and spinal cord is initiated in the earliest stages of mammalian pregnancy in a highly organized process known as neurulation. Convergent and extension movements transforms a flat sheet of ectodermal cells into a narrow and elongated line of neuroepithelia, while a major source of Sonic Hedgehog signaling from the notochord induces the overlying neuroepithelial cells t...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2c45626e-8b33-5faa-a936-b724dc002bad
DOI: 10.1101/2023.08.04.552068

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Disruption of Fuz in mouse embryos generates hypoplastic hindbrain development and reduced cranial nerve gangliaDOI 10.1101/2023.08.04.552068Read

Neurulation in the cranial region--normal and abnormal.Semantic proximity Read

Pathogenesis of neural tube defects: The regulation and disruption of cellular processes underlying neural tube closureSemantic proximity Read

The genetic basis of mammalian neurulation.Semantic proximity Read

Phenotypic Expansion and Molecular Implications in Recessive FUZ -Related Ciliopathy.Semantic proximity Read

Genetics and development of neural tube defectsSemantic proximity Read

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure.Semantic proximity Read

Neural tube defects—disorders of neurulation and related embryonic processesSemantic proximity Read

Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes.Semantic proximity Read

Further characterization of the genetic defect of the Bent tail mouse, a mouse model for human neural tube defects.Semantic proximity Read

Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes.Semantic proximity Read

ZFP423 regulates early patterning and multiciliogenesis in the hindbrain choroid plexusSemantic proximity Read

Absence of posterior commissure and sub-commissural organ precedes encephalocele development in a new mouse modelSemantic proximity Read