Article

The Ciliopathy Gene <i>Ftm/Rpgrip1l</i> Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling

2018-09-04

Abstract excerpt

<h4>ABSTRACT</h4> Primary cilia are essential for central nervous system development. In the mouse, they play a critical role in patterning the spinal cord and telencephalon via the regulation of Hedgehog/Gli signaling. However, despite the frequent disruption of this signaling pathway in human forebrain malformations, the role of primary cilia in forebrain morphogenesis has been little investigated outside the t...

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Literature Corpus work: dc3e7574-e477-5846-b42b-397924c4bc5d
DOI: 10.1101/408120

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