Article
Golgi-localized, gamma-ear-containing, Arf-binding protein adaptors mediate insulin-responsive trafficking of glucose transporter 4 in 3T3-L1 adipocytes.
Molecular endocrinology (Baltimore, Md.) - 1 Aug 2005
Li Lin V, Kandror Konstantin V
Abstract excerpt
Small glucose transporter 4 (Glut4)-containing vesicles represent the major insulin-responsive compartment in fat and skeletal muscle cells. The molecular mechanism of their biogenesis is not yet elucidated. Here, we studied the role of the newly discovered family of monomeric adaptor proteins, G...
Topics
- 3T3-L1 Cells
- ADP-Ribosylation Factors
- Adaptor Proteins, Vesicular Transport
- Adipocytes
- Adsorption
- Animals
- Cell Membrane
- Cell-Free System
- DNA, Complementary
- Electroporation
- Genes, Dominant
- Glucose Transport Proteins, Facilitative
- Glutathione Transferase
- Golgi Apparatus
- Immunoblotting
- Immunohistochemistry
- Insulin
- Mice