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The adhesion G protein‐coupled receptor VLGR1/ADGRV1 controls autophagy

1 Apr 2023

Abstract excerpt

VLGR1/ADGRV1 (very large G protein-coupled receptor-1) is the largest known adhesion G protein-coupled receptor. Mutations in VLGR1/ADGRV1 cause Usher syndrome (USH), the most common form of hereditary deaf-blindness, and have been additionally linked to epilepsy. Although VLGR1/ADGRV1 is almost ubiquitously expressed, little is known about the subcellular function and signalling of the VLGR1 protein and thus...

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PMID: 37002809
DOI: 10.1111/bcpt.13869

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