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Article

Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain.

Nature structural biology - 1 Jul 2002

Nogi Terukazu, Shiba Yoko, Kawasaki Masato, Shiba Tomoo, Matsugaki Naohiro, Igarashi Noriyuki, Suzuki Mamoru, Kato Ryuichi, Takatsu Hiroyuki, Nakayama Kazuhisa, Wakatsuki Soichi

Abstract excerpt

The adaptor proteins AP-1 and GGA regulate membrane traffic between the trans-Golgi network (TGN) and endosomes/lysosomes through ARF-regulated membrane association, recognition of sorting signals, and recruitment of clathrin and accessory proteins. The gamma 1-adaptin subunits of AP-1 and GGA possess homologous ear domains involved in the recruitment of accessory proteins, gamma-synergin and Rabaptin-5. The...

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Identifiers

PMID: 12042876
DOI: 10.1038/nsb808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain.PMID 12042876Read ↗

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