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Article

A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome.

The Journal of cell biology - 3 Apr 2000

Hirst J, Lui W W, Bright N A, Totty N, Seaman M N, Robinson M S

Abstract excerpt

We have cloned and characterized members of a novel family of proteins, the GGAs. These proteins contain an NH(2)-terminal VHS domain, one or two coiled-coil domains, and a COOH-terminal domain homologous to the COOH-terminal "ear" domain of gamma-adaptin. However, unlike gamma-adaptin, the GGAs are not associated with clathrin-coated vesicles or with any of the components of the AP-1 complex. GGA1 and GGA2 are...

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Share to Adaptor Proteins, Vesicular Transport
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Cathepsin A

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Source

Open in PubMed Open full text

Identifiers

PMID: 10747088
DOI: 10.1083/jcb.149.1.67
PMCID: PMC2175106

Genes

GGA1
GGA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome.PMID 10747088Read ↗

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