Article

The adhesion G-protein coupled receptor VLGR1/ADGRV1 controls autophagy

2023-01-04

Abstract excerpt

VLGR1/ADGRV1 (very large G protein-coupled receptor-1) is the largest known adhesion G protein-coupled receptor. Mutations in VLGR1/ADGRV1 cause Usher syndrome (USH), the most common form of hereditary deaf-blindness, and have been additionally linked to epilepsy. Although VLGR1/ADGRV1 is almost ubiquitously expressed, little is known about the subcellular function and signalling of the VLGR1 protein and thus abou...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9dc20bcc-da90-5b3f-935b-d936f6c7f780
DOI: 10.22541/au.167285899.97082645/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The adhesion G-protein coupled receptor VLGR1/ADGRV1 controls autophagyDOI 10.22541/au.167285899.97082645/v1Read

The adhesion G protein‐coupled receptor VLGR1/ADGRV1 controls autophagySemantic proximity Read

Affinity Proteomics Identifies Interaction Partners and Defines Novel Insights into the Function of the Adhesion GPCR VLGR1/ADGRV1Semantic proximity Read

Adhesion G protein-coupled receptor VLGR1/ADGRV1 regulates cell spreading and migration by mechanosensing at focal adhesionsSemantic proximity Read

The adhesion GPCR VLGR1/ADGRV1 regulates focal adhesion turnover by controlling their assemblySemantic proximity Read

The adhesion GPCR ADGRV1 controls glutamate homeostasis in hippocampal astrocytes supporting neuron development: first insights into to pathophysiology of <i>ADGRV1</i> -associated epilepsySemantic proximity Read

Studies on the very large G protein-coupled receptor: from initial discovery to determining its role in sensorineural deafness in higher animals.Semantic proximity Read

Structural insights into the inactive state of the adhesion GPCR ADGRV1Semantic proximity Read

Endocytic Adaptor Proteins in Health and Disease: Lessons from Model Organisms and Human Mutations.Semantic proximity Read

Roles of VMP1 in Autophagy and ER–Membrane Contact: Potential Implications in Neurodegenerative DisordersSemantic proximity Read

EVA1A Plays an Important Role by Regulating Autophagy in Physiological and Pathological ProcessesSemantic proximity Read

The BBS/CCT chaperonin complex ensures the localization of the adhesion G protein-coupled receptor ADGRV1 to primary ciliaSemantic proximity Read

Pathophysiological impact of the adhesion G protein-coupled receptor familySemantic proximity Read