Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Rab4 effector Rabip4 plays a role in the endocytotic trafficking of Glut 4 in 3T3-L1 adipocytes.

Journal of cell science - 1 Apr 2006

Mari Muriel, Monzo Pascale, Kaddai Vincent, Keslair Frédérique, Gonzalez Teresa, Le Marchand-Brustel Yannick, Cormont Mireille

Abstract excerpt

Insulin regulates glucose uptake in the adipocytes by modulating Glut 4 localization, a traffic pathway involving the endocytic small GTPases Rab4, Rab5, and RabThe expression of the Rab4 effector Rabip4 leads to a 30% increase in glucose uptake and Glut 4 translocation in the presence of insulin, without modifications in the basal condition. This effect was not due to modifications of Glut 4 expression or...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3T3-L1 Cells
Share to Adipocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Compartmentation

Share to Fluorescein-5-isothiocyanate

Share to Fluorescent Dyes

Share to Glucose Transporter Type 4

Share to Subcellular Fractions

Share to Transferrin

Source

Identifiers

PMID: 16522682
DOI: 10.1242/jcs.02850

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Rab4 effector Rabip4 plays a role in the endocytotic trafficking of Glut 4 in 3T3-L1 adipocytes.PMID 16522682Read ↗

Rab10 in insulin-stimulated GLUT4 translocation.Semantic proximity Read ↗

Expression of a prenylation-deficient Rab4 inhibits the GLUT4 translocation induced by active phosphatidylinositol 3-kinase and protein kinase B.Semantic proximity Read ↗

The small guanosine triphosphate-binding protein Rab4 is involved in insulin-induced GLUT4 translocation and actin filament rearrangement in 3T3-L1 cells.Semantic proximity Read ↗

GLUT4 is sorted to vesicles whose accumulation beneath and insertion into the plasma membrane are differentially regulated by insulin and selectively affected by insulin resistance.Semantic proximity Read ↗

Rab 3D in rat adipose cells and its overexpression in genetic obesity (Zucker fatty rat).Semantic proximity Read ↗

Golgi-localized, gamma-ear-containing, Arf-binding protein adaptors mediate insulin-responsive trafficking of glucose transporter 4 in 3T3-L1 adipocytes.Semantic proximity Read ↗

Rabs 8A and 14 are targets of the insulin-regulated Rab-GAP AS160 regulating GLUT4 traffic in muscle cells.Semantic proximity Read ↗

Cell-autonomous adiposity through increased cell surface GLUT4 due to ankyrin-B deficiency.Semantic proximity Read ↗

Roles of 1-phosphatidylinositol 3-kinase and ras in regulating translocation of GLUT4 in transfected rat adipose cells.Semantic proximity Read ↗

Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation.Semantic proximity Read ↗

Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation.Semantic proximity Read ↗

Direct interaction of Rab4 with syntaxin 4.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.