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Article

Genetic selection for high acute inflammatory response confers resistance to lung carcinogenesis in the mouse.

Experimental lung research - 1 Jan 2000

Ribeiro Orlando Garcia, Cabrera Wafa Hanna, Maria Durvanei Augusto, De Franco Marcelo, Massa Solange, Di Pace Roberto Francisco, de Souza Vinicius Ricardo Cuña, Starobinas Nancy, Semen Michel, Ibañez Olga Martinez

Abstract excerpt

Mice selected for a high acute inflammatory response (AIRmax) are resistant to chemically induced lung tumorigenesis, whereas the low responders (AIRmin) are susceptible. In urethane-treated mice, anti-inflammatory drugs increased the tumor incidence in AIRmax but not AIRmin mice, and an inverse correlation (P<.001) between the degree of acute inflammatory response (AIR) and lung tumorigenesis was found in an F2...

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Source

Identifiers

PMID: 15765921
DOI: 10.1080/01902140490495237

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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