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Article

Mapping of novel loci involved in lung and colon tumor susceptibility by the use of genetically selected mouse strains.

Genes and immunity - 1 Feb 2022

Borrego Andrea, Jensen José Ricardo, Cabrera Wafa Hanna Koury, Massa Solange, Ribeiro Orlando Garcia, Starobinas Nancy, De Franco Marcelo, Eto Silas Fernandes, Manenti Giacomo, Dragani Tommaso Antonio, Ibañez Olga Martinez

Abstract excerpt

Two non-inbred mouse lines, phenotypically selected for maximal (AIRmin) and minimal (AIRmax) acute inflammatory response, show differential susceptibility/resistance to the development of several chemically-induced tumor types. An intercross pedigree of these mice was generated and treated with the chemical carcinogen dimethylhydrazine, which induces lung and intestinal tumors. Genome wide high-density...

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Identifiers

PMID: 34966170
DOI: 10.1038/s41435-021-00159-z
PMCID: PMC8866122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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