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Article

Resistance to melanoma metastases in mice selected for high acute inflammatory response.

Carcinogenesis - 1 Feb 2001

Maria D A, Ribeiro O G, Pizzocaro K F, De Franco M, Cabrera W K, Starobinas N, Gallois V, Siqueira M, Seman M, Ibañez O M

Abstract excerpt

The role of innate immunity in natural resistance to tumor progression was investigated in two mouse lines, AIRmax and AIRmin, selected by bi-directional selective breeding on the basis of high or low acute inflammatory response. Compared with AIRmin, AIRmax mice were shown to be resistant to 7,12-dimethylbenz[a]anthracene (DMBA)/12-O:-tetradecanoylphorbol-13-acetate-induced skin cancers and here we demonstrate...

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Identifiers

PMID: 11181457
DOI: 10.1093/carcin/22.2.337

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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