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Article

Genetic linkage analysis identifies Pas1 as the common locus modulating lung tumorigenesis and acute inflammatory response in mice.

Genes and immunity - 1 Dec 2013

Galvan A, Cabrera W, Vorraro F, Jensen J R, Borrego A, Starobinas N, Ribeiro O G, De Franco M, Knott S, Dragani T A, Manenti G, Ibañez O C M

Abstract excerpt

Selective breeding for the acute inflammatory response (AIR) generated two mouse lines characterized by maximum (AIRmax) and minimum (AIRmin) responses, explained by the additive effect of alleles differentially fixed in quantitative trait loci (QTLs). These mice also differ in their susceptibility to lung tumorigenesis, raising the possibility that the same loci are involved in the control of both phenotypes. To...

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Source

Identifiers

PMID: 24067788
DOI: 10.1038/gene.2013.49

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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