Article
Inverse genetic predisposition to colon versus lung carcinogenesis in mouse lines selected based on acute inflammatory responsiveness.
Carcinogenesis - 1 Aug 2006
Di Pace Roberto Francisco, Massa Solange, Ribeiro Orlando Garcia, Cabrera Wafa Hanna Koury, De Franco Marcelo, Starobinas Nancy, Seman Michel, Ibañez Olga Célia Martinez
Abstract excerpt
Mouse lines produced by bidirectional selection on the basis of maximum (AIRmax) or minimum (AIRmin) acute inflammatory reactions were examined for the development of chemically induced acute colitis and colon tumors and the development of lung tumors. AIRmax mice were more susceptible than AIRmi...
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