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Article

Lack of ras mutations and prediction of long-term survival in carcinoma of the colon.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Mar 1992

Halter S A, Webb L, Rose J

Abstract excerpt

Ras oncogene mutations are found in a significant number of human colonic carcinomas. Correlation between patient survival and ras mutations was explored and compared with other clinical parameters. Colonic carcinoma embedded in paraffin was subjected to the polymerase chain reaction using primers to amplify codon 12 of the K-ras oncogene. Oligonucleotide probes to six mutations were used to identify mutated...

Topics

Adult
Aged
Aged, 80 and over
Carcinoma
Colonic Neoplasms
Female
Genes, ras
Humans
Male
Middle Aged
Mutation
Neoplasm Staging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymerase Chain Reaction

Survival Analysis

Time Factors

Source

Identifiers

PMID: 1574489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1574489-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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