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Article

Detection of mutated K12-ras in histologically negative lymph nodes as an indicator of poor prognosis in stage II colorectal cancer.

Clinical colorectal cancer - 1 Aug 2001

Belly R T, Rosenblatt J D, Steinmann M, Toner J, Sun J, Shehadi J, Peacock J L, Raubertas R F, Jani N, Ryan C K

Abstract excerpt

Stage II colorectal carcinoma is characterized by negative lymph node pathology as determined by conventional microscopic examination. These patients generally do not receive adjuvant therapy although 20%-30% will die from metastatic disease. To determine whether K-ras mutations at codon 12 could be used as a sensitive indicator of occult lymph node metastasis in stage II colon carcinoma, a retrospective study...

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Identifiers

PMID: 12445369
DOI: 10.3816/CCC.2001.n.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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