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Article

Can K-ras gene mutation be utilized as prognostic biomarker for colorectal cancer patients receiving chemotherapy? A meta-analysis and systematic review.

PloS one - 1 Jan 2013

Rui Yuan-Yi, Zhang Dan, Zhou Zong-Guang, Wang Cun, Yang Lie, Yu Yong-Yang, Chen Hai-Ning

Abstract excerpt

INTRODUCTION: K-ras gene mutations were common in colorectal patients, but their relationship with prognosis was unclear. OBJECTIVE: Verify prognostic differences between patient with and without mutant K-ras genes by reviewing the published evidence. METHOD: Systematic reviews and data bases were searched for cohort/case-control studies of prognosis of colorectal cancer patients with detected K-ras mutations...

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Identifiers

PMID: 24205021
DOI: 10.1371/journal.pone.0077901
PMCID: PMC3804628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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