The prognostic value of the presence of mutations at the codons 12, 13, 61 of K-ras oncogene in colorectal cancer.

Article

The prognostic value of the presence of mutations at the codons 12, 13, 61 of K-ras oncogene in colorectal cancer.

Anticancer research - 1 Jan 2000

Pajkos G, Kiss I, Sándor J, Ember I, Kisházi P

Abstract excerpt

The predictive and prognostic value of the c-K-ras mutation is still unequivocal despite extensive and intensive studies. Investigation of the occurrence of mutations in 88 colorectal cancer patients' specimens using the polymerase chain reaction (PCR) is reported: age: 61.9 years (27-80), gender...

Topics

Biomarkers, Tumor
Codon
Colorectal Neoplasms
Female
Genes, ras
Genetic Markers
Humans
Male
Mutation
Prognosis
Survival Analysis

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