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Article

Stability of K-ras mutations throughout the natural history of human colorectal cancer.

European journal of cancer (Oxford, England : 1990) - 1 Jan 1992

Losi L, Benhattar J, Costa J

Abstract excerpt

We have used a rapid, non-radioactive and sensitive method based on allele-specific amplification using the polymerase chain reaction for the identification of K-ras mutations in archival tissues of colorectal carcinomas. Our purpose was to determine whether or not K-ras mutation provides, when present, a tumour marker throughout the natural history of the disease. We have studied 35 patients who developed...

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Identifiers

PMID: 1627381
DOI: 10.1016/0959-8049(92)90468-h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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