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Article

Clinical usefulness of K-RAS mutation detection in colorectal cancer and in surgical margins of the colon.

Roczniki Akademii Medycznej w Bialymstoku (1995) - 1 Jan 2004

Okulczyk B, Kovalchuk O, Piotrowski Z, Myśliwiec P, Chyczewski L

Abstract excerpt

The incidence of K-RAS gene mutations in tumour and surgical margins was investigated in 63 patients with adenocarcinomas of varied clinical stage and histological grade. Point mutations of codon 12 K-RAS gene were detected, using the PCR-RFPL technique in cancer tissue in 23 patients (36.5%) and in colon margin mucosa in 1 patient (3.7%), out of 27 examined subjects. No significant correlations were found...

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PMID: 15638373

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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