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Article

Clinical usefulness of K-RAS mutation detection in colorectal cancer and in surgical margins of the colon.

Roczniki Akademii Medycznej w Bialymstoku (1995) - 1 Jan 2004

Okulczyk B, Kovalchuk O, Piotrowski Z, Myśliwiec P, Chyczewski L

Abstract excerpt

The incidence of K-RAS gene mutations in tumour and surgical margins was investigated in 63 patients with adenocarcinomas of varied clinical stage and histological grade. Point mutations of codon 12 K-RAS gene were detected, using the PCR-RFPL technique in cancer tissue in 23 patients (36.5%) and...

Topics

Colon
Colonic Neoplasms
Colorectal Neoplasms
DNA Primers
DNA, Neoplasm
Genes, ras
Humans
Mutation
Polymerase Chain Reaction

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 15638373

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15638373-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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