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Article

CYP1A1 Val462 and NQO1 Ser187 polymorphisms, cigarette use, and risk for colorectal adenoma.

Carcinogenesis - 1 Jun 2005

Hou Lifang, Chatterjee Nilanjan, Huang Wen-Yi, Baccarelli Andrea, Yadavalli Sunita, Yeager Meredith, Bresalier Robert S, Chanock Stephen J, Caporaso Neil E, Ji Bu-Tian, Weissfeld Joel L, Hayes Richard B

Abstract excerpt

Cigarette use is a risk factor for colorectal adenoma, a known precursor of colorectal cancer. Polymorphic variants in NQO1 and CYP1A1 influence the activation of carcinogenic substances in tobacco smoke, possibly impacting on tobacco-associated risks for colorectal tumors. We investigated the association of cigarette smoking with risk for advanced colorectal adenoma in relation to the CYP1A1 Val(462) and NQO1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15731166
DOI: 10.1093/carcin/bgi054

Genes

NQO1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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