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Article

CYP1A1, cigarette smoking, and colon and rectal cancer.

American journal of epidemiology - 1 Nov 2004

Slattery Martha L, Samowtiz W, Ma K, Murtaugh M, Sweeney C, Levin T R, Neuhausen S

Abstract excerpt

Cytochrome P-450 (CYP) is involved in the activation and metabolism of polycyclic aromatic hydrocarbons in tobacco products. The authors evaluated the association of two polymorphisms in the CYP1A1 gene--the noncoding Msp I polymorphism in the 3'-untranslated region and the Ile462Val polymorphism in exon 7--with colon and rectal cancer. The authors used data from two incident case-control studies of colon cancer...

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Source

Identifiers

PMID: 15496536
DOI: 10.1093/aje/kwh298

Genes

GSTM1
NAT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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