Article
Contribution of NAD(P)H quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and risk of colorectal adenoma and colorectal cancer in Caucasians: a meta-analysis.
Archives of medical research - 1 Jan 2012
Chen Jing, Lin Yuan, Zhang Ru, Huang Zhi-jie, Pan Xing-guo
Abstract excerpt
BACKGROUND AND AIMS: The effects of polymorphism of NAD(P)H quinone oxidoreductase 1 (NQO1 Pro187Ser, rs1800566) on the risks of colorectal adenoma and cancer have been widely studied and results remain controversial. Therefore, the aim of this meta-analysis was to quantitatively assess the relationships. METHODS: Databases of Medline, Embase and Wanfang were retrieved until May 15, 2011. Pooled odds ratio (OR)...
Topics
- Adenoma
- Case-Control Studies
- Colorectal Neoplasms
- Genetic Association Studies
- Humans
- Linear Models
- Mutation, Missense
- NAD(P)H Dehydrogenase (Quinone)