Article
Differences in viral and host genetic risk factors for development of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis between Iranian and Japanese HTLV-1-infected individuals.
The Journal of general virology - 1 Mar 2005
Sabouri Amir H, Saito Mineki, Usuku Koichiro, Bajestan Sepideh Naghibzadeh, Mahmoudi Mahmoud, Forughipour Mohsen, Sabouri Zahra, Abbaspour Zahra, Goharjoo Mohammad E, Khayami Esmaeil, Hasani Ali, Izumo Shuji, Arimura Kimiyoshi, Farid Reza, Osame Mitsuhiro
Abstract excerpt
Human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurological disease observed only in 1-2 % of infected individuals. HTLV-1 provirus load, certain HLA alleles and HTLV-1 tax subgroups are reported to be associated with different levels of risk for HAM/TSP in Kagoshima, Japan. Here, it was determined whether these risk factors were also valid for...
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