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Article

Effects of host restriction factors and the HTLV-1 subtype on susceptibility to HTLV-1-associated myelopathy/tropical spastic paraparesis.

Retrovirology - 19 Apr 2017

Nozuma Satoshi, Matsuura Eiji, Kodama Daisuke, Tashiro Yuichi, Matsuzaki Toshio, Kubota Ryuji, Izumo Shuji, Takashima Hiroshi

Abstract excerpt

BACKGROUND: Although human T-lymphotropic virus type 1 (HTLV-1) infection is a prerequisite for the development of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), specific provirus mutations in HAM/TSP have not yet been reported. In this study, we examined whether HAM/TSP patients had the disease-specific genomic variants of HTLV-1 by analyzing entire sequences of HTLV-1 proviruses in these...

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Identifiers

PMID: 28420387
DOI: 10.1186/s12977-017-0350-9
PMCID: PMC5395872

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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