Article
HLA-G 3'-untranslated region polymorphisms are associated with HTLV-1 infection, proviral load and HTLV-associated myelopathy/tropical spastic paraparesis development.
The Journal of general virology - 1 Oct 2016
Cilião Alves Daiani Cristina, Haddad Rodrigo, Rocha-Júnior Maurício Cristiano, de Deus Wagatsuma Virgínia Mara, Martelli-Palomino Gustavo, Marques Adriana Aparecida, Takayanagui Osvaldo Massaiti, Covas Dimas Tadeu, Kashima Simone, Donadi Eduardo Antônio
Abstract excerpt
Most human T-lymphotropic virus type 1 (HTLV-1)-infected patients remain asymptomatic throughout life. The factors associated with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) development have not been fully elucidated; immunological and genetic factors may be involved. The association of 14 bp INS/DEL HLA-G polymorphism with HTLV-1 infection susceptibility has been reported previously....
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