Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of HLA class I alleles and heterozygosity on the outcome of human T cell lymphotropic virus type I infection.

Journal of immunology (Baltimore, Md. : 1950) - 15 Dec 2000

Jeffery K J, Siddiqui A A, Bunce M, Lloyd A L, Vine A M, Witkover A D, Izumo S, Usuku K, Welsh K I, Osame M, Bangham C R

Abstract excerpt

The inflammatory disease human T cell lymphotropic virus type I (HTLV-I)-associated myelopathy (HAM/TSP) occurs in only 1-2% of HTLV-I-infected individuals and is associated with a high provirus load of HTLV-I. We hypothesize that a person's risk of developing HAM/TSP depends upon the efficiency of their immune response to the virus, which differs between individuals because of polymorphism in genes that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, MHC Class I
Share to Genetic Carrier Screening

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-A2 Antigen

Share to HLA-B Antigens

Share to HLA-C Antigens

Share to Human T-lymphotropic virus 1

Share to Paraparesis, Tropical Spastic

Share to Proviruses

Source

Identifiers

PMID: 11120862
DOI: 10.4049/jimmunol.165.12.7278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of HLA class I alleles and heterozygosity on the outcome of human T cell lymphotropic virus type I infection.PMID 11120862Read ↗

HLA class I alleles in HTLV-1-associated myelopathy and asymptomatic carriers from the Brazilian cohort GIPH.Semantic proximity Read ↗

HLA alleles determine human T-lymphotropic virus-I (HTLV-I) proviral load and the risk of HTLV-I-associated myelopathy.Semantic proximity Read ↗

Polygenic control of human T lymphotropic virus type I (HTLV-I) provirus load and the risk of HTLV-I-associated myelopathy/tropical spastic paraparesis.Semantic proximity Read ↗

The influence of human leukocyte antigen class I loci -A, -B, -C, and class II HLA-DRB1 alleles in a Brazilian HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) population and association with disease outcome and proviral loadSemantic proximity Read ↗

Differences in viral and host genetic risk factors for development of human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis between Iranian and Japanese HTLV-1-infected individuals.Semantic proximity Read ↗

Association between HLA alleles and HAM/TSP in individuals infected with HTLV-1.Semantic proximity Read ↗

Genome wide association study of HTLV-1-associated myelopathy/tropical spastic paraparesis in the Japanese population.Semantic proximity Read ↗

HLA-G 3'-untranslated region polymorphisms are associated with HTLV-1 infection, proviral load and HTLV-associated myelopathy/tropical spastic paraparesis development.Semantic proximity Read ↗

Human T cell leukemia virus type I (HTLV-I) molecular genotypes and disease outcome.Semantic proximity Read ↗

HLA-B*35 as a new marker for susceptibility to Human T-cell Lymphotropic Virus type 1 (HTLV-1) Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) in patients living in ArgentinaSemantic proximity Read ↗

Human leukocyte antigen class II alleles associated with human T-cell lymphotropic virus type I infection and adult T-cell leukemia/lymphoma in a Black population.Semantic proximity Read ↗

Absence of consistent association between human leukocyte antigen-I and -II alleles and human T-lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis risk in an HTLV-1 French Afro-Caribbean population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.