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Article

Increased cyclin E expression may obviate the role of cyclin D1 during brain development in cyclin D1 knockout mice.

Journal of neurochemistry - 1 Mar 2005

Chen Zhiguo, Duan Rui-Sheng, Zhu Yu, Folkesson Ronnie, Albanese Chris, Winblad Bengt, Zhu Jie

Abstract excerpt

Cyclins D and E play critical roles during the G1 phase of mammalian cell division. Cyclin D1 expression is high and expected to play an important role during mouse brain development. However, in the present study, we found no difference in CNS morphology between cyclin D1 knockout (KO) and control wild-type mice at the ages of 1, 4 and 12 months. Analysis of protein expression in embryonic brains revealed that...

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Identifiers

PMID: 15715677
DOI: 10.1111/j.1471-4159.2004.02934.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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