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Article

Rescue of cyclin D1 deficiency by knockin cyclin E.

Cell - 11 Jun 1999

Geng Y, Whoriskey W, Park M Y, Bronson R T, Medema R H, Li T, Weinberg R A, Sicinski P

Abstract excerpt

D-type cyclins and cyclin E represent two very distinct classes of mammalian G1 cyclins. We have generated a mouse strain in which the coding sequences of the cyclin D1 gene (Ccnd1) have been deleted and replaced by those of human cyclin E (CCNE). In the tissues and cells of these mice, the expre...

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Cyclin D1
Cyclin E
Mice
Mice, Inbred C57BL
Phenotype
Receptors, Estrogen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 10380928
DOI: 10.1016/s0092-8674(00)80788-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10380928-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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