Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.

Nature - 21 Jan 2010

Bienvenu Frédéric, Jirawatnotai Siwanon, Elias Joshua E, Meyer Clifford A, Mizeracka Karolina, Marson Alexander, Frampton Garrett M, Cole Megan F, Odom Duncan T, Odajima Junko, Geng Yan, Zagozdzon Agnieszka, Jecrois Marie, Young Richard A, Liu X Shirley, Cepko Constance L, Gygi Steven P, Sicinski Piotr

Abstract excerpt

Cyclin D1 belongs to the core cell cycle machinery, and it is frequently overexpressed in human cancers. The full repertoire of cyclin D1 functions in normal development and oncogenesis is unclear at present. Here we developed Flag- and haemagglutinin-tagged cyclin D1 knock-in mouse strains that...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatin Immunoprecipitation
Share to CREB-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin D1

Share to High-Throughput Screening Assays

Share to Histone Acetyltransferases

Share to Mass Spectrometry

Share to Receptor, Notch1

Share to Retina

Source

Open in PubMed Open full text

Identifiers

PMID: 20090754
DOI: 10.1038/nature08684
PMCID: PMC2943587

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20090754-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen.PMID 20090754Read ↗

ChIP sequencing of cyclin D1 reveals a transcriptional role in chromosomal instability in miceSemantic proximity Read ↗

Cyclin-dependent kinases and rare developmental disordersSemantic proximity Read ↗

Proteomic Landscape of Tissue-Specific Cyclin E Functions in VivoSemantic proximity Read ↗

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.Semantic proximity Read ↗

Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis.Semantic proximity Read ↗

Nucleocytoplasmic functions of the PDZ‐LIM protein family: new insights into organ developmentSemantic proximity Read ↗

Loss of Pin1 function in the mouse causes phenotypes resembling cyclin D1-null phenotypes.Semantic proximity Read ↗

D-Type Cyclins in Development and DiseaseSemantic proximity Read ↗

Targeting Cyclins and Cyclin-Dependent Kinases in Cancer: Lessons from Mice, Hopes for Therapeutic Applications in HumansSemantic proximity Read ↗

Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling.Semantic proximity Read ↗

Cyclins and Cell Cycle Control in Cancer and DiseaseSemantic proximity Read ↗

Distinct and redundant functions of cyclin E1 and cyclin E2 in development and cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.